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A DNA test for L2-HGA in Staffordshire Bull Terriers.
What is L2-HGA?
DNA test for L2-HGA
Breeds at risk
Although L2-HGA probably affects more dog breeds, up to now only for
the Staffordshire Bull Terrier the genetic basis for the disorder was
identified. At this moment there is no clarity about the origin of the
defective allele. If the disorder was already present in one of the dog
populations that were used to develop the Stafford, the genetic disorder
could be present in more breeds originating from the same source.
In the past, when breeds were developed, often breeding stock of other
breeds was used to improve certain characteristics. In the process of
introducing the desired qualities (genes) into a breed, it cannot be
avoided that many neutral as well as many undesirable genes cross the
barrier between breeds. For the time being, in cases where similar
clinical symptoms are found in a breed with "family ties" with the
Staffordshire Bull Terrier, checking with the DNA test would be a "best guess".
If it can be proven that the defective allele is present, applying that
DNA test will help the breeders in their selection against the disorder.
From there on it is one out of two, solving an existing problem or preventing
a future breed problem from developing.
Breeding policy
Testing for L2-HGA
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