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A DNA test for CaniAne Leukocyte Adhesion Deficiency (CLAD)
What is CLAD?
A DNA test for CLAD
Breeds at risk
As far as we know until now, CLAD only affects Irish Setters and
Irish Red and White Setters. We should be aware that the disorder can
be found in related crossbred animals as well.
In the past, when breeds were developed, often breeding stock of other breeds
was used to improve certain characteristics. In the process of introducing the
desired qualities (genes) into a breed, it cannot be avoided that many neutral
as well as undesirable genes cross the barrier between breeds. For the time
being, in cases an immunodeficiency is found in a breed with "family ties"
with the Irish Setter and/or the Irish Red and White Setter,
checking with the CLAD DNA test could be a "best guess". If
it can be proven that the defective allele is present, applying that
DNA test will help the breeders in their selection against the disorder.
From there on it is one out of two, solving an existing breed problem or
preventing a future breed problem from developing.
Breeding policy
Testing for CLAD
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